IV. Aging well

IV. Aging well


Our chronological age, how old we are, often does not reflect our biological age

How old are you?

Biological age depends on both intrinsic or genetic factors and extrinsic factors such as diet, physical activity, use of harmful substances, stress and anxiety.

Unlike with chronological age, measuring biological age is neither simple nor immediate.

Telomeres and the epigenetic clock are molecular markers that can determine biological age. Both are contained in our DNA.

Biological age
can be
greater than, less than or the same
as chronological age


Telomeres were the first molecular markers described. They are fragments of repeated DNA which are found at the ends of chromosomes.

Telomeres can be shortened with cell division, such that the measurement of their shortening can be an indicator of biological age.

The epigenetic clock.

Another newly described molecular mechanism is the so-called epigenetic clock, which can estimate biological age more accurately than telomeres. They are chemical markers that appear on DNA and they change with age based on our lifestyle.

Find out how the epigenetic clock works.

Our chronological age does not always reflect our biological age.

If you eat a balanced diet, do physical and intellectual activity, lead a quiet life, etc., your biological age can be less than your chronological age.

If you take care of yourself
If you take care of yourself a little
If you don’t take care of yourself
Biological age
Chronological age

Que mecanismos
determinam a minha idade biológica?

View answer

O processo de envelhecimento em humanos, entendido como a perda de funções corporais acompanhada de uma degeneração geral de células e tecidos, surge da decadência progressiva do potencial das células-mãe adultas.

Os fatores implicados no processo podem ser internos (genéticos) e externos (ambientais, estilos de vida, etc.).

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